Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms

The establishment and maintenance of apical-basal polarity is a defining characteristic and essential feature of functioning epithelia. Apical-basal polarity (ABP) proteins are also tumor suppressors that are targeted for disruption by oncogenic viruses and are commonly mutated in human carcinomas....

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Detalles Bibliográficos
Autores principales: Schimizzi, Gregory V., Maher, Meghan T., Loza, Andrew J., Longmore, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959776/
https://www.ncbi.nlm.nih.gov/pubmed/27454609
http://dx.doi.org/10.1371/journal.pone.0159881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959776/
https://www.ncbi.nlm.nih.gov/pubmed/27454609
http://dx.doi.org/10.1371/journal.pone.0159881

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