Gentisic acid sodium salt, a phenolic compound, is superior to norepinephrine in reversing cardiovascular collapse, hepatic mitochondrial dysfunction and lactic acidemia in Pseudomonas aeruginosa septic shock in dogs

BACKGROUND: The development of lactic acidemia (LA) in septic shock (SS) is associated with an ominous prognosis. We previously showed that the mechanism of LA in SS may relate to impaired hepatic uptake of lactate, but the mechanism was not clear. Uptake of lactate by the liver occurs by a membrane...

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Detalles Bibliográficos
Autores principales: Mink, Steven, Roy Chowdhury, Subir K., Gotes, Jose, Cheng, Zhao-Qin, Kasian, Krika, Fernyhough, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960072/
https://www.ncbi.nlm.nih.gov/pubmed/27456956
http://dx.doi.org/10.1186/s40635-016-0095-0

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