Age-Related Decrease in Heat Shock 70-kDa Protein 8 in Cerebrospinal Fluid Is Associated with Increased Oxidative Stress

Age-associated declines in protein homeostasis mechanisms (“proteostasis”) are thought to contribute to age-related neurodegenerative disorders. The increased oxidative stress which occurs with aging can activate a key proteostatic process, chaperone-mediated autophagy. This study investigated age-r...

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Detalles Bibliográficos
Autores principales: Loeffler, David A., Klaver, Andrea C., Coffey, Mary P., Aasly, Jan O., LeWitt, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960228/
https://www.ncbi.nlm.nih.gov/pubmed/27507943
http://dx.doi.org/10.3389/fnagi.2016.00178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960228/
https://www.ncbi.nlm.nih.gov/pubmed/27507943
http://dx.doi.org/10.3389/fnagi.2016.00178

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