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Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells

Development of cervical squamous cell carcinoma requires increased expression of the major high-risk human-papillomavirus (HPV) oncogenes E6 and E7 in basal cervical epithelial cells. We used a systems biology approach to identify host transcriptional networks in such cells and study the concentrati...

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Detalles Bibliográficos
Autores principales:	Smith, Stephen P., Scarpini, Cinzia G., Groves, Ian J., Odle, Richard I., Coleman, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960560/ https://www.ncbi.nlm.nih.gov/pubmed/27457222 http://dx.doi.org/10.1038/srep29832

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