ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells

Glioma cells with stem cell traits are thought to be responsible for tumor maintenance and therapeutic failure. Such cells can be enriched based on their inherent drug efflux capability mediated by the ABC transporter ABCG2 using the side population assay, and their characteristics include increased...

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Detalles Bibliográficos
Autores principales: Wee, Boyoung, Pietras, Alexander, Ozawa, Tatsuya, Bazzoli, Elena, Podlaha, Ondrej, Antczak, Christophe, Westermark, Bengt, Nelander, Sven, Uhrbom, Lene, Forsberg-Nilsson, Karin, Djaballah, Hakim, Michor, Franziska, Holland, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960591/
https://www.ncbi.nlm.nih.gov/pubmed/27456282
http://dx.doi.org/10.1038/srep25956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960591/
https://www.ncbi.nlm.nih.gov/pubmed/27456282
http://dx.doi.org/10.1038/srep25956

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