Autocrine activity of BDNF induced by the STAT3 signaling pathway causes prolonged TrkB activation and promotes human non-small-cell lung cancer proliferation

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin superfamily, which has been implicated in the pathophysiology of the nervous system. Recently, several studies have suggested that BDNF and/or its receptor, tropomyosin related kinase B (TrkB), are involved in tumor growth and...

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Detalles Bibliográficos
Autores principales: Chen, Bo, Liang, Yan, He, Zheng, An, Yunhe, Zhao, Weihong, Wu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960652/
https://www.ncbi.nlm.nih.gov/pubmed/27456333
http://dx.doi.org/10.1038/srep30404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960652/
https://www.ncbi.nlm.nih.gov/pubmed/27456333
http://dx.doi.org/10.1038/srep30404

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