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Predictive value of vrk 1 and 2 for rectal adenocarcinoma response to neoadjuvant chemoradiation therapy: a retrospective observational cohort study

BACKGROUND: Neoadjuvant chemoradiotherapy (NACRT) followed by surgical resection is the standard therapy for locally advanced rectal cancer. However, tumor response following NACRT varies, ranging from pathologic complete response to disease progression. We evaluated the kinases VRK1 and VRK2, which...

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Detalles Bibliográficos
Autores principales: del Puerto-Nevado, Laura, Marin-Arango, Juan Pablo, Fernandez-Aceñero, Maria Jesus, Arroyo-Manzano, David, Martinez-Useros, Javier, Borrero-Palacios, Aurea, Rodriguez-Remirez, Maria, Cebrian, Arancha, Gomez del Pulgar, Teresa, Cruz-Ramos, Marlid, Carames, Cristina, Lopez-Botet, Begoña, Garcia-Foncillas, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960836/
https://www.ncbi.nlm.nih.gov/pubmed/27456229
http://dx.doi.org/10.1186/s12885-016-2574-9