Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs

BACKGROUND: Glioblastoma stem cells (GSC) have been extensively recognized as a plausible cause of glioblastoma resistance to therapy and recurrence resulting in high glioblastoma mortality. Abnormalities in the DNA repair pathways might be responsible for the inability of the currently used chemoth...

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Detalles Bibliográficos
Autores principales: Kenig, Saša, Faoro, Valentina, Bourkoula, Evgenia, Podergajs, Neža, Ius, Tamara, Vindigni, Marco, Skrap, Miran, Lah, Tamara, Cesselli, Daniela, Storici, Paola, Vindigni, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960855/
https://www.ncbi.nlm.nih.gov/pubmed/27462186
http://dx.doi.org/10.1186/s12935-016-0339-9

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