p53-independent structure-activity relationships of 3-ring mesogenic compounds’ activity as cytotoxic effects against human non-small cell lung cancer lines

BACKGROUND: We recently demonstrated the cytotoxicity of liquid crystal precursors (hereafter referred to as “mesogenic compounds”) in the human non-small cell lung cancer (NSCLC) cell line A549 which carry wild-type p53. p53 mutations are observed in 50 % of NSCLC and contribute to their resistance...

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Detalles Bibliográficos
Autores principales: Fukushi, Saori, Yoshino, Hironori, Yoshizawa, Atsushi, Kashiwakura, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960859/
https://www.ncbi.nlm.nih.gov/pubmed/27456853
http://dx.doi.org/10.1186/s12885-016-2585-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960859/
https://www.ncbi.nlm.nih.gov/pubmed/27456853
http://dx.doi.org/10.1186/s12885-016-2585-6

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