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Hyperthermia induced HIF-1a expression of lung cancer through AKT and ERK signaling pathways
BACKGROUND: Hyperthermia is a promising treatment for human lung cancer, but recurrence of the primary lesion is common, as the residual tumor becomes adapted to heat treatment and growth is induced by hypoxia-triggered HIF-1a expression. Here, we explored the effects of hyperthermia on HIF-1a expre...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960890/ https://www.ncbi.nlm.nih.gov/pubmed/27456341 http://dx.doi.org/10.1186/s13046-016-0399-7 |