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Benzo(a)pyrene Is Mutagenic in Mouse Spermatogonial Stem Cells and Dividing Spermatogonia

Although many environmental agents are established male germ cell mutagens, few are known to induce mutations in spermatogonial stem cells. Stem cell mutations are of great concern because they result in a permanent increase in the number of mutations carried in sperm. We investigated mutation induc...

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Detalles Bibliográficos
Autores principales:	O’Brien, Jason M., Beal, Marc A., Yauk, Carole L., Marchetti, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Mutagenic Effects of Benzo(a)pyrene in Mouse Sperm Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960908/ https://www.ncbi.nlm.nih.gov/pubmed/27208087 http://dx.doi.org/10.1093/toxsci/kfw088

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