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Adult medulloblastoma: A rare case report and literature review
BACKGROUND: Medulloblastoma is a highly malignant embryonal tumor which commonly arises in the cerebellum. It is relatively rare and accounts for less than 2% of all primary brain tumors. The tumor primarily occurs in childhood; however, rarely, it may be found in adult population. In addition, medu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960923/ https://www.ncbi.nlm.nih.gov/pubmed/27512610 http://dx.doi.org/10.4103/2152-7806.185782 |
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author | Faried, Ahmad Pribadi, Muhammad A. Sumargo, Sheila Arifin, Muhammad Z. Hernowo, Bethy S. |
author_facet | Faried, Ahmad Pribadi, Muhammad A. Sumargo, Sheila Arifin, Muhammad Z. Hernowo, Bethy S. |
author_sort | Faried, Ahmad |
collection | PubMed |
description | BACKGROUND: Medulloblastoma is a highly malignant embryonal tumor which commonly arises in the cerebellum. It is relatively rare and accounts for less than 2% of all primary brain tumors. The tumor primarily occurs in childhood; however, rarely, it may be found in adult population. In addition, medulloblastoma in adult population shows features which are quite distinct from the pediatric group. CASE DESCRIPTION: We report the case of a 33-year-old man who presented to our institution with a history of blurred vision of both eyes for 5 months preceded by intermittent headache since the previous year. Preoperative investigation suggested a posterior fossa mass and we suspected an ependymoma. The patient underwent ventriculoperitoneal shunt and craniotomy tumor removal, followed by radiotherapy. Histopathological and immunohistochemical examination were performed, and the results showed a diagnosis of medulloblastoma. CONCLUSION: This case is exceptional because adult medulloblastoma occurrence in our center is extremely rare, and the diagnosis can only be established through histopathological and immunohistochemical studies. |
format | Online Article Text |
id | pubmed-4960923 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-49609232016-08-10 Adult medulloblastoma: A rare case report and literature review Faried, Ahmad Pribadi, Muhammad A. Sumargo, Sheila Arifin, Muhammad Z. Hernowo, Bethy S. Surg Neurol Int Surgical Neurology International: Neuro-Oncology BACKGROUND: Medulloblastoma is a highly malignant embryonal tumor which commonly arises in the cerebellum. It is relatively rare and accounts for less than 2% of all primary brain tumors. The tumor primarily occurs in childhood; however, rarely, it may be found in adult population. In addition, medulloblastoma in adult population shows features which are quite distinct from the pediatric group. CASE DESCRIPTION: We report the case of a 33-year-old man who presented to our institution with a history of blurred vision of both eyes for 5 months preceded by intermittent headache since the previous year. Preoperative investigation suggested a posterior fossa mass and we suspected an ependymoma. The patient underwent ventriculoperitoneal shunt and craniotomy tumor removal, followed by radiotherapy. Histopathological and immunohistochemical examination were performed, and the results showed a diagnosis of medulloblastoma. CONCLUSION: This case is exceptional because adult medulloblastoma occurrence in our center is extremely rare, and the diagnosis can only be established through histopathological and immunohistochemical studies. Medknow Publications & Media Pvt Ltd 2016-07-07 /pmc/articles/PMC4960923/ /pubmed/27512610 http://dx.doi.org/10.4103/2152-7806.185782 Text en Copyright: © 2016 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Surgical Neurology International: Neuro-Oncology Faried, Ahmad Pribadi, Muhammad A. Sumargo, Sheila Arifin, Muhammad Z. Hernowo, Bethy S. Adult medulloblastoma: A rare case report and literature review |
title | Adult medulloblastoma: A rare case report and literature review |
title_full | Adult medulloblastoma: A rare case report and literature review |
title_fullStr | Adult medulloblastoma: A rare case report and literature review |
title_full_unstemmed | Adult medulloblastoma: A rare case report and literature review |
title_short | Adult medulloblastoma: A rare case report and literature review |
title_sort | adult medulloblastoma: a rare case report and literature review |
topic | Surgical Neurology International: Neuro-Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960923/ https://www.ncbi.nlm.nih.gov/pubmed/27512610 http://dx.doi.org/10.4103/2152-7806.185782 |
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