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Adult medulloblastoma: A rare case report and literature review

BACKGROUND: Medulloblastoma is a highly malignant embryonal tumor which commonly arises in the cerebellum. It is relatively rare and accounts for less than 2% of all primary brain tumors. The tumor primarily occurs in childhood; however, rarely, it may be found in adult population. In addition, medu...

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Autores principales: Faried, Ahmad, Pribadi, Muhammad A., Sumargo, Sheila, Arifin, Muhammad Z., Hernowo, Bethy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960923/
https://www.ncbi.nlm.nih.gov/pubmed/27512610
http://dx.doi.org/10.4103/2152-7806.185782
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author Faried, Ahmad
Pribadi, Muhammad A.
Sumargo, Sheila
Arifin, Muhammad Z.
Hernowo, Bethy S.
author_facet Faried, Ahmad
Pribadi, Muhammad A.
Sumargo, Sheila
Arifin, Muhammad Z.
Hernowo, Bethy S.
author_sort Faried, Ahmad
collection PubMed
description BACKGROUND: Medulloblastoma is a highly malignant embryonal tumor which commonly arises in the cerebellum. It is relatively rare and accounts for less than 2% of all primary brain tumors. The tumor primarily occurs in childhood; however, rarely, it may be found in adult population. In addition, medulloblastoma in adult population shows features which are quite distinct from the pediatric group. CASE DESCRIPTION: We report the case of a 33-year-old man who presented to our institution with a history of blurred vision of both eyes for 5 months preceded by intermittent headache since the previous year. Preoperative investigation suggested a posterior fossa mass and we suspected an ependymoma. The patient underwent ventriculoperitoneal shunt and craniotomy tumor removal, followed by radiotherapy. Histopathological and immunohistochemical examination were performed, and the results showed a diagnosis of medulloblastoma. CONCLUSION: This case is exceptional because adult medulloblastoma occurrence in our center is extremely rare, and the diagnosis can only be established through histopathological and immunohistochemical studies.
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spelling pubmed-49609232016-08-10 Adult medulloblastoma: A rare case report and literature review Faried, Ahmad Pribadi, Muhammad A. Sumargo, Sheila Arifin, Muhammad Z. Hernowo, Bethy S. Surg Neurol Int Surgical Neurology International: Neuro-Oncology BACKGROUND: Medulloblastoma is a highly malignant embryonal tumor which commonly arises in the cerebellum. It is relatively rare and accounts for less than 2% of all primary brain tumors. The tumor primarily occurs in childhood; however, rarely, it may be found in adult population. In addition, medulloblastoma in adult population shows features which are quite distinct from the pediatric group. CASE DESCRIPTION: We report the case of a 33-year-old man who presented to our institution with a history of blurred vision of both eyes for 5 months preceded by intermittent headache since the previous year. Preoperative investigation suggested a posterior fossa mass and we suspected an ependymoma. The patient underwent ventriculoperitoneal shunt and craniotomy tumor removal, followed by radiotherapy. Histopathological and immunohistochemical examination were performed, and the results showed a diagnosis of medulloblastoma. CONCLUSION: This case is exceptional because adult medulloblastoma occurrence in our center is extremely rare, and the diagnosis can only be established through histopathological and immunohistochemical studies. Medknow Publications & Media Pvt Ltd 2016-07-07 /pmc/articles/PMC4960923/ /pubmed/27512610 http://dx.doi.org/10.4103/2152-7806.185782 Text en Copyright: © 2016 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Surgical Neurology International: Neuro-Oncology
Faried, Ahmad
Pribadi, Muhammad A.
Sumargo, Sheila
Arifin, Muhammad Z.
Hernowo, Bethy S.
Adult medulloblastoma: A rare case report and literature review
title Adult medulloblastoma: A rare case report and literature review
title_full Adult medulloblastoma: A rare case report and literature review
title_fullStr Adult medulloblastoma: A rare case report and literature review
title_full_unstemmed Adult medulloblastoma: A rare case report and literature review
title_short Adult medulloblastoma: A rare case report and literature review
title_sort adult medulloblastoma: a rare case report and literature review
topic Surgical Neurology International: Neuro-Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960923/
https://www.ncbi.nlm.nih.gov/pubmed/27512610
http://dx.doi.org/10.4103/2152-7806.185782
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