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Inhibition of c-Jun N-terminal Kinase Signaling Pathway Alleviates Lipopolysaccharide-induced Acute Respiratory Distress Syndrome in Rats

BACKGROUND: An acute respiratory distress syndrome (ARDS) is still one of the major challenges in critically ill patients. This study aimed to investigate the effect of inhibiting c-Jun N-terminal kinase (JNK) on ARDS in a lipopolysaccharide (LPS)-induced ARDS rat model. METHODS: Thirty-six rats wer...

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Detalles Bibliográficos
Autores principales: Lai, Jian-Bo, Qiu, Chun-Fang, Chen, Chuan-Xi, Chen, Min-Ying, Chen, Juan, Guan, Xiang-Dong, Ouyang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960963/
https://www.ncbi.nlm.nih.gov/pubmed/27411461
http://dx.doi.org/10.4103/0366-6999.185867