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Structures of multidrug and toxic compound extrusion transporters and their mechanistic implications
Multidrug resistance poses grand challenges to the effective treatment of infectious diseases and cancers. Integral membrane proteins from the multidrug and toxic compound extrusion (MATE) family contribute to multidrug resistance by exporting a wide variety of therapeutic drugs across cell membrane...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960993/ https://www.ncbi.nlm.nih.gov/pubmed/26488689 http://dx.doi.org/10.1080/19336950.2015.1106654 |