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Beneficial Effects of Berberine on Oxidized LDL-Induced Cytotoxicity to Human Retinal Müller Cells

PURPOSE: Limited mechanistic understanding of diabetic retinopathy (DR) has hindered therapeutic advances. Berberine, an isoquinolone alkaloid, has shown favorable effects on glucose and lipid metabolism in animal and human studies, but effects on DR are unknown. We previously demonstrated intrareti...

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Detalles Bibliográficos
Autores principales: Fu, Dongxu, Yu, Jeremy Y., Connell, Anna R., Yang, Shihe, Hookham, Michelle B., McLeese, Rebecca, Lyons, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961062/
https://www.ncbi.nlm.nih.gov/pubmed/27367504
http://dx.doi.org/10.1167/iovs.16-19291