Population Exposure‐Response Modeling of Naloxegol in Patients With Noncancer‐Related Pain and Opioid‐Induced Constipation

Naloxegol is a polyethylene glycol derivative of naloxone approved in the US as a once‐daily oral treatment for opioid‐induced constipation (OIC) in adults with chronic noncancer pain. Population exposure–response models were constructed based on data from two phase III studies comprising 1,331 adul...

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Detalles Bibliográficos
Autores principales: Al‐Huniti, N, Nielsen, JC, Hutmacher, MM, Lappalainen, J, Cantagallo, K, Sostek, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961079/
https://www.ncbi.nlm.nih.gov/pubmed/27435972
http://dx.doi.org/10.1002/psp4.12099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961079/
https://www.ncbi.nlm.nih.gov/pubmed/27435972
http://dx.doi.org/10.1002/psp4.12099

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