Pathological relationships involving iron and myelin may constitute a shared mechanism linking various rare and common brain diseases

We previously demonstrated elevated brain iron levels in myelinated structures and associated cells in a hemochromatosis Hfe(−/−)xTfr2(mut) mouse model. This was accompanied by altered expression of a group of myelin-related genes, including a suite of genes causatively linked to the rare disease fa...

Descripción completa

Detalles Bibliográficos
Autores principales: Heidari, Moones, Gerami, Sam H., Bassett, Brianna, Graham, Ross M., Chua, Anita C.G., Aryal, Ritambhara, House, Michael J., Collingwood, Joanna F., Bettencourt, Conceição, Houlden, Henry, Ryten, Mina, Olynyk, John K., Trinder, Debbie, Johnstone, Daniel M., Milward, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961263/
https://www.ncbi.nlm.nih.gov/pubmed/27500074
http://dx.doi.org/10.1080/21675511.2016.1198458

Ejemplares similares

Ejemplares similares