Resveratrol Inhibits Aortic Root Dilatation in the Fbn1(C1039G/+) Marfan Mouse Model

OBJECTIVE—: Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the fibrillin-1 gene. Patients with MFS are at risk of aortic aneurysm formation and dissection. Usually, blood pressure–lowering drugs are used to reduce aortic events; however, this is not sufficient for most...

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Detalles Bibliográficos
Autores principales: Hibender, Stijntje, Franken, Romy, van Roomen, Cindy, ter Braake, Anique, van der Made, Ingeborg, Schermer, Edith E., Gunst, Quinn, van den Hoff, Maurice J., Lutgens, Esther, Pinto, Yigal M., Groenink, Maarten, Zwinderman, Aeilko H., Mulder, Barbara J.M., de Vries, Carlie J.M., de Waard, Vivian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961273/
https://www.ncbi.nlm.nih.gov/pubmed/27283746
http://dx.doi.org/10.1161/ATVBAHA.116.307841

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