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Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K−Akt/p-HDAC6 Signaling Pathway

OBJECTIVE—: Cathepsin S (CatS) participates in atherogenesis through several putative mechanisms. The ability of cathepsins to modify histone tail is likely to contribute to stem cell development. Histone deacetylase 6 (HDAC6) is required in modulating the proliferation and migration of various type...

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Detalles Bibliográficos
Autores principales:	Wu, Hongxian, Cheng, Xian Wu, Hu, Lina, Takeshita, Kyosuke, Hu, Chen, Du, Qiuna, Li, Xiang, Zhu, Enbo, Huang, Zhe, Yisireyili, Maimaiti, Zhao, Guangxian, Piao, Limei, Inoue, Aiko, Jiang, Haiying, Lei, Yanna, Zhang, Xiaohong, Liu, Shaowen, Dai, Qiuyan, Kuzuya, Masafumi, Shi, Guo-Ping, Murohara, Toyoaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2016
Materias:	Basic Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961274/ https://www.ncbi.nlm.nih.gov/pubmed/27365406 http://dx.doi.org/10.1161/ATVBAHA.115.307110

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