Cargando…

Hyperuricemia-Related Diseases and Xanthine Oxidoreductase (XOR) Inhibitors: An Overview

Uric acid is the final oxidation product of purine metabolism in humans. Xanthine oxidoreductase (XOR) catalyzes oxidative hydroxylation of hypoxanthine to xanthine to uric acid, accompanying the production of reactive oxygen species (ROS). Uric acid usually forms ions and salts known as urates and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Changyi, Lü, Jian-Ming, Yao, Qizhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2016
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961276/ https://www.ncbi.nlm.nih.gov/pubmed/27423335 http://dx.doi.org/10.12659/MSM.899852

Ejemplares similares

The Role of Oxidative Stress in Hyperuricemia and Xanthine Oxidoreductase (XOR) Inhibitors
por: Liu, Ning, et al.
Publicado: (2021)

Plasma Xanthine Oxidoreductase (XOR) Activity in Cardiovascular Disease Outpatients
por: Matsushita, Masato, et al.
Publicado: (2020)

Mechanistic insights into xanthine oxidoreductase from development studies of candidate drugs to treat hyperuricemia and gout
por: Nishino, Takeshi, et al.
Publicado: (2014)

Pro-Aging Effects of Xanthine Oxidoreductase Products
por: Battelli, Maria Giulia, et al.
Publicado: (2020)

Xanthine oxidoreductase: A leading actor in cardiovascular disease drama
por: Polito, Letizia, et al.
Publicado: (2021)

Metabolic syndrome and cancer risk: The role of xanthine oxidoreductase
por: Battelli, Maria Giulia, et al.
Publicado: (2018)

Xanthine oxidoreductase: One enzyme for multiple physiological tasks
por: Bortolotti, Massimo, et al.
Publicado: (2021)

Evaluation of Neuronal Protective Effects of Xanthine Oxidoreductase Inhibitors on Severe Whole-brain Ischemia in Mouse Model and Analysis of Xanthine Oxidoreductase Activity in the Mouse Brain
por: SUZUKI, Go, et al.
Publicado: (2015)

Xanthine oxidoreductase activity is correlated with hepatic steatosis
por: Yagi, Chisako, et al.
Publicado: (2022)

Discriminating Susceptibility of Xanthine Oxidoreductase Family to Metals
por: Steunou, Anne-Soisig, et al.
Publicado: (2023)

Xanthine Oxidoreductase-Derived Reactive Species: Physiological and Pathological Effects
por: Battelli, Maria Giulia, et al.
Publicado: (2016)

Mutations Associated with Functional Disorder of Xanthine Oxidoreductase and Hereditary Xanthinuria in Humans
por: Ichida, Kimiyoshi, et al.
Publicado: (2012)

Association of Mutations Identified in Xanthinuria with the Function and Inhibition Mechanism of Xanthine Oxidoreductase
por: Sekine, Mai, et al.
Publicado: (2021)

Influence of xanthine oxidoreductase inhibitor, topiroxostat, on body weight of diabetic obese mice
por: Nakamura, Takashi, et al.
Publicado: (2021)

Pharmacodynamic evaluation of the XOR inhibitor WN1703 in a model of chronic hyperuricemia in rats induced by yeast extract combined with potassium oxonate
por: Li, Yuanyuan, et al.
Publicado: (2022)

Diurnal Variations in Serum Uric Acid, Xanthine, and Xanthine Oxidoreductase Activity in Male Patients with Coronary Artery Disease
por: Shimizu, Megumi, et al.
Publicado: (2023)

Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities
por: Harmon, Daniel B., et al.
Publicado: (2019)

Putting xanthine oxidoreductase and aldehyde oxidase on the NO metabolism map: Nitrite reduction by molybdoenzymes()
por: Maia, Luisa B., et al.
Publicado: (2018)

Chemical Nature and Reaction Mechanisms of the Molybdenum Cofactor of Xanthine Oxidoreductase
por: Okamoto, Ken, et al.
Publicado: (2013)

Xanthine oxidoreductase in cancer: more than a differentiation marker
por: Battelli, Maria Giulia, et al.
Publicado: (2015)

Allopurinol and oxypurinol differ in their strength and mechanisms of inhibition of xanthine oxidoreductase
por: Sekine, Mai, et al.
Publicado: (2023)

Comprehensive analysis of the relationship between xanthine oxidoreductase activity and chronic kidney disease
por: Zhang, Yiyuan, et al.
Publicado: (2023)

Human Plasma Xanthine Oxidoreductase Activity in Cardiovascular Disease: Evidence from a Population-Based Study
por: Kotozaki, Yuka, et al.
Publicado: (2023)

Evaluation of the Effectiveness of Xanthine Oxidoreductase Inhibitors on Haemodialysis Patients using a Marginal Structural Model
por: Ishii, Takeo, et al.
Publicado: (2017)

Inhibition of Xanthine Oxidoreductase Enhances the Potential of Tyrosine Kinase Inhibitors against Chronic Myeloid Leukemia
por: Romo-González, Marta, et al.
Publicado: (2020)

On the Sparsity of XORs in Approximate Model Counting
por: Agrawal, Durgesh, et al.
Publicado: (2020)

Xanthine oxidoreductase-catalyzed reactive species generation: A process in critical need of reevaluation()
por: Cantu-Medellin, Nadiezhda, et al.
Publicado: (2013)

Independent links between plasma xanthine oxidoreductase activity and levels of adipokines
por: Furuhashi, Masato, et al.
Publicado: (2019)

Hydrogen sulfide stimulates xanthine oxidoreductase conversion to nitrite reductase and formation of NO
por: Pardue, Sibile, et al.
Publicado: (2020)

Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage
por: Nasi, Sonia, et al.
Publicado: (2021)

Febuxostat, a novel xanthine oxidoreductase inhibitor, improves hypertension and endothelial dysfunction in spontaneously hypertensive rats
por: Shirakura, Takashi, et al.
Publicado: (2016)

Xanthine Oxidoreductase Inhibitor Use Associated With Reduced Risk of Sarcopenia and Severe Sarcopenia in Patients Undergoing Hemodialysis
por: Kurajoh, Masafumi, et al.
Publicado: (2022)

Hyperuricaemia, Xanthine Oxidoreductase and Ribosome-Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research
por: Bolognesi, Andrea, et al.
Publicado: (2017)

Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia
por: Gao, Tianshu, et al.
Publicado: (2022)

Xanthine Oxidoreductase in Drug Metabolism: Beyond a Role as a  Detoxifying Enzyme
por: Battelli, Maria Giulia, et al.
Publicado: (2016)

Xanthine Oxidoreductase Reference Values in Platelet-Poor Plasma and Platelets in Healthy Volunteers
por: Cecerska-Heryć, Elżbieta, et al.
Publicado: (2015)

Gender Differences in the Impact of Plasma Xanthine Oxidoreductase Activity on Coronary Artery Spasm
por: Watanabe, Ken, et al.
Publicado: (2021)

Tissue xanthine oxidoreductase activity in a mouse model of aristolochic acid nephropathy
por: Ishii, Takeo, et al.
Publicado: (2021)

Xanthine oxidoreductase gene polymorphisms are associated with high risk of sepsis and organ failure
por: Gao, Li, et al.
Publicado: (2023)

Relationship between Xanthine Oxidoreductase Redox and Oxidative Stress among Chronic Kidney Disease Patients
por: Terawaki, Hiroyuki, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rcub14931bh97iql3job19n4d5