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MicroRNA-145 Mediates Steroid-Induced Necrosis of the Femoral Head by Targeting the OPG/RANK/RANKL Signaling Pathway

OBJECTIVE: To investigate the role of microRNA-145 (miR-145) in steroid-induced necrosis of the femoral head (SINFH) by evaluating its effects on the OPG/RANK/RANKL signaling pathway. METHODS: A rat model of SINFH was constructed via injection of the lentiviral vector pLV-shRNA-miR-145. Pathological...

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Detalles Bibliográficos
Autores principales:	Zhao, Ji-Jun, Wu, Zhao-Feng, Wang, Ling, Feng, De-Hong, Cheng, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961289/ https://www.ncbi.nlm.nih.gov/pubmed/27459539 http://dx.doi.org/10.1371/journal.pone.0159805

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