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The hydroxypyridinone iron chelator CP94 increases methyl-aminolevulinate-based photodynamic cell killing by increasing the generation of reactive oxygen species

Methyl-aminolevulinate-based photodynamic therapy (MAL-PDT) is utilised clinically for the treatment of non-melanoma skin cancers and pre-cancers and the hydroxypyridinone iron chelator, CP94, has successfully been demonstrated to increase MAL-PDT efficacy in an initial clinical pilot study. However...

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Detalles Bibliográficos
Autores principales:	Dogra, Yuktee, Ferguson, Daniel C.J., Dodd, Nicholas J.F., Smerdon, Gary R., Curnow, Alison, Winyard, Paul G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961297/ https://www.ncbi.nlm.nih.gov/pubmed/27454766 http://dx.doi.org/10.1016/j.redox.2016.07.002

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