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Caging and Uncaging Genetics

It is important for biology to understand if observations made in highly reductionist laboratory settings generalise to harsh and noisy natural environments in which genetic variation is sorted to produce adaptation. But what do we learn by studying, in the laboratory, a genetically diverse populati...

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Detalles Bibliográficos
Autores principales: Little, Tom J., Colegrave, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961361/
https://www.ncbi.nlm.nih.gov/pubmed/27458971
http://dx.doi.org/10.1371/journal.pbio.1002525
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author Little, Tom J.
Colegrave, Nick
author_facet Little, Tom J.
Colegrave, Nick
author_sort Little, Tom J.
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description It is important for biology to understand if observations made in highly reductionist laboratory settings generalise to harsh and noisy natural environments in which genetic variation is sorted to produce adaptation. But what do we learn by studying, in the laboratory, a genetically diverse population that mirrors the wild? What is the best design for studying genetic variation? When should we consider it at all? The right experimental approach depends on what you want to know.
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spelling pubmed-49613612016-08-08 Caging and Uncaging Genetics Little, Tom J. Colegrave, Nick PLoS Biol Essay It is important for biology to understand if observations made in highly reductionist laboratory settings generalise to harsh and noisy natural environments in which genetic variation is sorted to produce adaptation. But what do we learn by studying, in the laboratory, a genetically diverse population that mirrors the wild? What is the best design for studying genetic variation? When should we consider it at all? The right experimental approach depends on what you want to know. Public Library of Science 2016-07-26 /pmc/articles/PMC4961361/ /pubmed/27458971 http://dx.doi.org/10.1371/journal.pbio.1002525 Text en © 2016 Little, Colegrave http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Essay
Little, Tom J.
Colegrave, Nick
Caging and Uncaging Genetics
title Caging and Uncaging Genetics
title_full Caging and Uncaging Genetics
title_fullStr Caging and Uncaging Genetics
title_full_unstemmed Caging and Uncaging Genetics
title_short Caging and Uncaging Genetics
title_sort caging and uncaging genetics
topic Essay
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961361/
https://www.ncbi.nlm.nih.gov/pubmed/27458971
http://dx.doi.org/10.1371/journal.pbio.1002525
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