A Novel Bufalin Derivative Exhibited Stronger Apoptosis-Inducing Effect than Bufalin in A549 Lung Cancer Cells and Lower Acute Toxicity in Mice

BF211 is a synthetic molecule derived from bufalin (BF). The apoptosis-inducing effect of BF211 was stronger than that of BF while the acute toxicity of BF211 was much lower than that of BF. BF211 exhibited promising concentration-dependent anti-cancer effects in nude mice inoculated with A549 cells...

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Detalles Bibliográficos
Autores principales: Liu, Miao, Feng, Li-Xing, Sun, Peng, Liu, Wang, Wu, Wan-Ying, Jiang, Bao-Hong, Yang, Min, Hu, Li-Hong, Guo, De-An, Liu, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961401/
https://www.ncbi.nlm.nih.gov/pubmed/27459387
http://dx.doi.org/10.1371/journal.pone.0159789

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