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Decoding RAS isoform and codon-specific signalling

RAS proteins are key signalling hubs that are oncogenically mutated in 30% of all cancer cases. Three genes encode almost identical isoforms that are ubiquitously expressed, but are not functionally redundant. The network responses associated with each isoform and individual oncogenic mutations rema...

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Detalles Bibliográficos
Autores principales:	Newlaczyl, Anna U., Hood, Fiona E., Coulson, Judy M., Prior, Ian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2014
Materias:	Biochemical Society Focused Meetings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961500/ https://www.ncbi.nlm.nih.gov/pubmed/25109951 http://dx.doi.org/10.1042/BST20140057

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