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Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii

Guanylate binding proteins (GBPs) are a family of large interferon‐inducible GTPases that are transcriptionally upregulated upon infection with intracellular pathogens. Murine GBPs (mGBPs) including mGBP1 and 2 localize to and disrupt pathogen‐containing vacuoles (PVs) resulting in the cell‐autonomo...

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Detalles Bibliográficos
Autores principales:	Johnston, Ashleigh C., Piro, Anthony, Clough, Barbara, Siew, Malvin, Virreira Winter, Sebastian, Coers, Jörn, Frickel, Eva‐Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Breaking Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961618/ https://www.ncbi.nlm.nih.gov/pubmed/26874079 http://dx.doi.org/10.1111/cmi.12579

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