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Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
PURPOSE: To evaluate the relationships between optic nerve head (ONH) blood flow by laser speckle flowgraphy (LSFG), and postmenstrual age and body weight in normal neonates. METHODS: During their normal sleep, we studied 24 infants (postmenstrual age, 248–295 days) whose ocular blood flow could be...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961725/ https://www.ncbi.nlm.nih.gov/pubmed/27118037 http://dx.doi.org/10.1007/s00417-016-3362-6 |
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author | Matsumoto, Tadashi Itokawa, Takashi Shiba, Tomoaki Katayama, Yuuji Arimura, Tetsushi Hine, Kotaro Mizukaki, Norio Yoda, Hitoshi Hori, Yuichi |
author_facet | Matsumoto, Tadashi Itokawa, Takashi Shiba, Tomoaki Katayama, Yuuji Arimura, Tetsushi Hine, Kotaro Mizukaki, Norio Yoda, Hitoshi Hori, Yuichi |
author_sort | Matsumoto, Tadashi |
collection | PubMed |
description | PURPOSE: To evaluate the relationships between optic nerve head (ONH) blood flow by laser speckle flowgraphy (LSFG), and postmenstrual age and body weight in normal neonates. METHODS: During their normal sleep, we studied 24 infants (postmenstrual age, 248–295 days) whose ocular blood flow could be measured three consecutive times. While the subjects slept in the supine position, three mean blur rate (MBR) values of the ONH were obtained: the MBR-A (mean of all values), MBR-V (vessel mean) and MBR-T (tissue mean) in the ONH. With regard to eye diseases, no retinopathy of prematurity (ROP) was observed, and no severe systemic diseases requiring treatment were noted in the subjects. Pearson’s correlation coefficients were used to determine the relationship between the MBR-A, −V, −T and postmenstrual age (days) and body weight (g). RESULTS: Postmenstrual age was significantly correlated with MBR-A (r = 0.64, p = 0.0007), MBR-V (r = 0.62, p = 0.0012) and MBR-T (r = 0.62, p = 0.0012). However, the body weight was not correlated with the MBR (MBR-A: r = 0.37, p = 0.07, MBR-V: r = 0.31, p = 0.14, MBR-T: r = 0.38, p = 0.06). CONCLUSIONS: Our results clarified that the values of ocular blood flow measured by LSFG correlate with the postmenstrual age of normal neonates. |
format | Online Article Text |
id | pubmed-4961725 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-49617252016-08-08 Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates Matsumoto, Tadashi Itokawa, Takashi Shiba, Tomoaki Katayama, Yuuji Arimura, Tetsushi Hine, Kotaro Mizukaki, Norio Yoda, Hitoshi Hori, Yuichi Graefes Arch Clin Exp Ophthalmol Pediatrics PURPOSE: To evaluate the relationships between optic nerve head (ONH) blood flow by laser speckle flowgraphy (LSFG), and postmenstrual age and body weight in normal neonates. METHODS: During their normal sleep, we studied 24 infants (postmenstrual age, 248–295 days) whose ocular blood flow could be measured three consecutive times. While the subjects slept in the supine position, three mean blur rate (MBR) values of the ONH were obtained: the MBR-A (mean of all values), MBR-V (vessel mean) and MBR-T (tissue mean) in the ONH. With regard to eye diseases, no retinopathy of prematurity (ROP) was observed, and no severe systemic diseases requiring treatment were noted in the subjects. Pearson’s correlation coefficients were used to determine the relationship between the MBR-A, −V, −T and postmenstrual age (days) and body weight (g). RESULTS: Postmenstrual age was significantly correlated with MBR-A (r = 0.64, p = 0.0007), MBR-V (r = 0.62, p = 0.0012) and MBR-T (r = 0.62, p = 0.0012). However, the body weight was not correlated with the MBR (MBR-A: r = 0.37, p = 0.07, MBR-V: r = 0.31, p = 0.14, MBR-T: r = 0.38, p = 0.06). CONCLUSIONS: Our results clarified that the values of ocular blood flow measured by LSFG correlate with the postmenstrual age of normal neonates. Springer Berlin Heidelberg 2016-04-27 2016 /pmc/articles/PMC4961725/ /pubmed/27118037 http://dx.doi.org/10.1007/s00417-016-3362-6 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Pediatrics Matsumoto, Tadashi Itokawa, Takashi Shiba, Tomoaki Katayama, Yuuji Arimura, Tetsushi Hine, Kotaro Mizukaki, Norio Yoda, Hitoshi Hori, Yuichi Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates |
title | Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates |
title_full | Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates |
title_fullStr | Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates |
title_full_unstemmed | Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates |
title_short | Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates |
title_sort | ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961725/ https://www.ncbi.nlm.nih.gov/pubmed/27118037 http://dx.doi.org/10.1007/s00417-016-3362-6 |
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