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Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates

PURPOSE: To evaluate the relationships between optic nerve head (ONH) blood flow by laser speckle flowgraphy (LSFG), and postmenstrual age and body weight in normal neonates. METHODS: During their normal sleep, we studied 24 infants (postmenstrual age, 248–295 days) whose ocular blood flow could be...

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Autores principales: Matsumoto, Tadashi, Itokawa, Takashi, Shiba, Tomoaki, Katayama, Yuuji, Arimura, Tetsushi, Hine, Kotaro, Mizukaki, Norio, Yoda, Hitoshi, Hori, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961725/
https://www.ncbi.nlm.nih.gov/pubmed/27118037
http://dx.doi.org/10.1007/s00417-016-3362-6
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author Matsumoto, Tadashi
Itokawa, Takashi
Shiba, Tomoaki
Katayama, Yuuji
Arimura, Tetsushi
Hine, Kotaro
Mizukaki, Norio
Yoda, Hitoshi
Hori, Yuichi
author_facet Matsumoto, Tadashi
Itokawa, Takashi
Shiba, Tomoaki
Katayama, Yuuji
Arimura, Tetsushi
Hine, Kotaro
Mizukaki, Norio
Yoda, Hitoshi
Hori, Yuichi
author_sort Matsumoto, Tadashi
collection PubMed
description PURPOSE: To evaluate the relationships between optic nerve head (ONH) blood flow by laser speckle flowgraphy (LSFG), and postmenstrual age and body weight in normal neonates. METHODS: During their normal sleep, we studied 24 infants (postmenstrual age, 248–295 days) whose ocular blood flow could be measured three consecutive times. While the subjects slept in the supine position, three mean blur rate (MBR) values of the ONH were obtained: the MBR-A (mean of all values), MBR-V (vessel mean) and MBR-T (tissue mean) in the ONH. With regard to eye diseases, no retinopathy of prematurity (ROP) was observed, and no severe systemic diseases requiring treatment were noted in the subjects. Pearson’s correlation coefficients were used to determine the relationship between the MBR-A, −V, −T and postmenstrual age (days) and body weight (g). RESULTS: Postmenstrual age was significantly correlated with MBR-A (r = 0.64, p = 0.0007), MBR-V (r = 0.62, p = 0.0012) and MBR-T (r = 0.62, p = 0.0012). However, the body weight was not correlated with the MBR (MBR-A: r = 0.37, p = 0.07, MBR-V: r = 0.31, p = 0.14, MBR-T: r = 0.38, p = 0.06). CONCLUSIONS: Our results clarified that the values of ocular blood flow measured by LSFG correlate with the postmenstrual age of normal neonates.
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spelling pubmed-49617252016-08-08 Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates Matsumoto, Tadashi Itokawa, Takashi Shiba, Tomoaki Katayama, Yuuji Arimura, Tetsushi Hine, Kotaro Mizukaki, Norio Yoda, Hitoshi Hori, Yuichi Graefes Arch Clin Exp Ophthalmol Pediatrics PURPOSE: To evaluate the relationships between optic nerve head (ONH) blood flow by laser speckle flowgraphy (LSFG), and postmenstrual age and body weight in normal neonates. METHODS: During their normal sleep, we studied 24 infants (postmenstrual age, 248–295 days) whose ocular blood flow could be measured three consecutive times. While the subjects slept in the supine position, three mean blur rate (MBR) values of the ONH were obtained: the MBR-A (mean of all values), MBR-V (vessel mean) and MBR-T (tissue mean) in the ONH. With regard to eye diseases, no retinopathy of prematurity (ROP) was observed, and no severe systemic diseases requiring treatment were noted in the subjects. Pearson’s correlation coefficients were used to determine the relationship between the MBR-A, −V, −T and postmenstrual age (days) and body weight (g). RESULTS: Postmenstrual age was significantly correlated with MBR-A (r = 0.64, p = 0.0007), MBR-V (r = 0.62, p = 0.0012) and MBR-T (r = 0.62, p = 0.0012). However, the body weight was not correlated with the MBR (MBR-A: r = 0.37, p = 0.07, MBR-V: r = 0.31, p = 0.14, MBR-T: r = 0.38, p = 0.06). CONCLUSIONS: Our results clarified that the values of ocular blood flow measured by LSFG correlate with the postmenstrual age of normal neonates. Springer Berlin Heidelberg 2016-04-27 2016 /pmc/articles/PMC4961725/ /pubmed/27118037 http://dx.doi.org/10.1007/s00417-016-3362-6 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Pediatrics
Matsumoto, Tadashi
Itokawa, Takashi
Shiba, Tomoaki
Katayama, Yuuji
Arimura, Tetsushi
Hine, Kotaro
Mizukaki, Norio
Yoda, Hitoshi
Hori, Yuichi
Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
title Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
title_full Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
title_fullStr Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
title_full_unstemmed Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
title_short Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
title_sort ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961725/
https://www.ncbi.nlm.nih.gov/pubmed/27118037
http://dx.doi.org/10.1007/s00417-016-3362-6
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