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Animal Models of Bone Loss in Inflammatory Arthritis: from Cytokines in the Bench to Novel Treatments for Bone Loss in the Bedside—a Comprehensive Review

Throughout life, bone is continuously remodelled. Bone is formed by osteoblasts, from mesenchymal origin, while osteoclasts induce bone resorption. This process is tightly regulated. During inflammation, several growth factors and cytokines are increased inducing osteoclast differentiation and activ...

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Detalles Bibliográficos
Autores principales: Alves, C. Henrique, Farrell, Eric, Vis, Marijn, Colin, Edgar M., Lubberts, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961736/
https://www.ncbi.nlm.nih.gov/pubmed/26634933
http://dx.doi.org/10.1007/s12016-015-8522-7