SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability

Although SIRT7 is a member of sirtuin family proteins that are described as NAD(+)-dependent class III histone deacetylases, the intrinsic enzymatic activity of this sirtuin protein remains to be investigated and the cellular function of SIRT7 remains to be explored. Here we report that SIRT7 is an...

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Detalles Bibliográficos
Autores principales: Li, Lei, Shi, Lan, Yang, Shangda, Yan, Ruorong, Zhang, Di, Yang, Jianguo, He, Lin, Li, Wanjin, Yi, Xia, Sun, Luyang, Liang, Jing, Cheng, Zhongyi, Shi, Lei, Shang, Yongfeng, Yu, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961794/
https://www.ncbi.nlm.nih.gov/pubmed/27436229
http://dx.doi.org/10.1038/ncomms12235

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