Glycolytic regulation of cell rearrangement in angiogenesis

During vessel sprouting, endothelial cells (ECs) dynamically rearrange positions in the sprout to compete for the tip position. We recently identified a key role for the glycolytic activator PFKFB3 in vessel sprouting by regulating cytoskeleton remodelling, migration and tip cell competitiveness. It...

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Detalles Bibliográficos
Autores principales: Cruys, Bert, Wong, Brian W., Kuchnio, Anna, Verdegem, Dries, Cantelmo, Anna Rita, Conradi, Lena-Christin, Vandekeere, Saar, Bouché, Ann, Cornelissen, Ivo, Vinckier, Stefan, Merks, Roeland M. H., Dejana, Elisabetta, Gerhardt, Holger, Dewerchin, Mieke, Bentley, Katie, Carmeliet, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961802/
https://www.ncbi.nlm.nih.gov/pubmed/27436424
http://dx.doi.org/10.1038/ncomms12240

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