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Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
Nanoparticle-mediated delivery of functional macromolecules is a promising method for treating a variety of human diseases. Among nanoparticles, cell-derived exosomes have recently been highlighted as a new therapeutic strategy for the in vivo delivery of nucleotides and chemical drugs. Here we desc...
Autores principales: | Yim, Nambin, Ryu, Seung-Wook, Choi, Kyungsun, Lee, Kwang Ryeol, Lee, Seunghee, Choi, Hojun, Kim, Jeongjin, Shaker, Mohammed R., Sun, Woong, Park, Ji-Ho, Kim, Daesoo, Do Heo, Won, Choi, Chulhee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961865/ https://www.ncbi.nlm.nih.gov/pubmed/27447450 http://dx.doi.org/10.1038/ncomms12277 |
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