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Dose-dependent effect of N'-Nitrosodiethylamine on hepatic architecture, RBC rheology and polypeptide repertoire in Wistar rats

N'-Nitrosodiethylamine (NDEA) is an effective hepatotoxicant, carcinogen and mutagen. NDEA-induced hepatic necrosis, through metabolic activation by CYP2E1, is an extensively used experimental model. In the present study, we analysed the dose- and time-dependent effect of NDEA on hepatic damage...

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Detalles Bibliográficos
Autores principales:	Mukherjee, Devoshree, Ahmad, Riaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Slovak Toxicology Society SETOX 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961919/ https://www.ncbi.nlm.nih.gov/pubmed/27486353 http://dx.doi.org/10.1515/intox-2015-0001

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