Stable preparations of tyrosine hydroxylase provide the solution structure of the full-length enzyme

Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the biosynthesis of catecholamine neurotransmitters. TH is a highly complex enzyme at mechanistic, structural, and regulatory levels, and the preparation of kinetically and conformationally stable enzyme for structural characterization ha...

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Detalles Bibliográficos
Autores principales: Bezem, Maria T., Baumann, Anne, Skjærven, Lars, Meyer, Romain, Kursula, Petri, Martinez, Aurora, Flydal, Marte I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961952/
https://www.ncbi.nlm.nih.gov/pubmed/27462005
http://dx.doi.org/10.1038/srep30390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961952/
https://www.ncbi.nlm.nih.gov/pubmed/27462005
http://dx.doi.org/10.1038/srep30390

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