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Community-Based Management of Child Malnutrition in Zambia: HIV/AIDS Infection and Other Risk Factors on Child Survival

(1) Background: Supplementary feeding programs (SFPs) are effective in the community-based treatment of moderate acute malnutrition (MAM) and prevention of severe acute malnutrition (SAM); (2) Methods: A retrospective study was conducted on a sample of 1266 Zambian malnourished children assisted fro...

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Autores principales: Moramarco, Stefania, Amerio, Giulia, Ciarlantini, Clarice, Chipoma, Jean Kasengele, Simpungwe, Matilda Kakungu, Nielsen-Saines, Karin, Palombi, Leonardo, Buonomo, Ersilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962207/
https://www.ncbi.nlm.nih.gov/pubmed/27376317
http://dx.doi.org/10.3390/ijerph13070666
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author Moramarco, Stefania
Amerio, Giulia
Ciarlantini, Clarice
Chipoma, Jean Kasengele
Simpungwe, Matilda Kakungu
Nielsen-Saines, Karin
Palombi, Leonardo
Buonomo, Ersilia
author_facet Moramarco, Stefania
Amerio, Giulia
Ciarlantini, Clarice
Chipoma, Jean Kasengele
Simpungwe, Matilda Kakungu
Nielsen-Saines, Karin
Palombi, Leonardo
Buonomo, Ersilia
author_sort Moramarco, Stefania
collection PubMed
description (1) Background: Supplementary feeding programs (SFPs) are effective in the community-based treatment of moderate acute malnutrition (MAM) and prevention of severe acute malnutrition (SAM); (2) Methods: A retrospective study was conducted on a sample of 1266 Zambian malnourished children assisted from 2012 to 2014 in the Rainbow Project SFPs. Nutritional status was evaluated according to WHO/Unicef methodology. We performed univariate and multivariate Cox proportional risk regression to identify the main predictors of mortality. In addition, a time-to event analysis was performed to identify predictors of failure and time to cure events; (3) Results: The analysis included 858 malnourished children (19 months ± 9.4; 49.9% males). Program outcomes met international standards with a better performance for MAM compared to SAM. Cox regression identified SAM (3.8; 2.1–6.8), HIV infection (3.1; 1.7–5.5), and WAZ <−3 (3.1; 1.6–5.7) as predictors of death. Time to event showed 80% of children recovered by SAM/MAM at 24 weeks. (4) Conclusions: Preventing deterioration of malnutrition, coupled to early detection of HIV/AIDS with adequate antiretroviral treatment, and extending the duration of feeding supplementation, could be crucial elements for ensuring full recovery and improve child survival in malnourished Zambian children.
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spelling pubmed-49622072016-08-01 Community-Based Management of Child Malnutrition in Zambia: HIV/AIDS Infection and Other Risk Factors on Child Survival Moramarco, Stefania Amerio, Giulia Ciarlantini, Clarice Chipoma, Jean Kasengele Simpungwe, Matilda Kakungu Nielsen-Saines, Karin Palombi, Leonardo Buonomo, Ersilia Int J Environ Res Public Health Article (1) Background: Supplementary feeding programs (SFPs) are effective in the community-based treatment of moderate acute malnutrition (MAM) and prevention of severe acute malnutrition (SAM); (2) Methods: A retrospective study was conducted on a sample of 1266 Zambian malnourished children assisted from 2012 to 2014 in the Rainbow Project SFPs. Nutritional status was evaluated according to WHO/Unicef methodology. We performed univariate and multivariate Cox proportional risk regression to identify the main predictors of mortality. In addition, a time-to event analysis was performed to identify predictors of failure and time to cure events; (3) Results: The analysis included 858 malnourished children (19 months ± 9.4; 49.9% males). Program outcomes met international standards with a better performance for MAM compared to SAM. Cox regression identified SAM (3.8; 2.1–6.8), HIV infection (3.1; 1.7–5.5), and WAZ <−3 (3.1; 1.6–5.7) as predictors of death. Time to event showed 80% of children recovered by SAM/MAM at 24 weeks. (4) Conclusions: Preventing deterioration of malnutrition, coupled to early detection of HIV/AIDS with adequate antiretroviral treatment, and extending the duration of feeding supplementation, could be crucial elements for ensuring full recovery and improve child survival in malnourished Zambian children. MDPI 2016-07-01 2016-07 /pmc/articles/PMC4962207/ /pubmed/27376317 http://dx.doi.org/10.3390/ijerph13070666 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Moramarco, Stefania
Amerio, Giulia
Ciarlantini, Clarice
Chipoma, Jean Kasengele
Simpungwe, Matilda Kakungu
Nielsen-Saines, Karin
Palombi, Leonardo
Buonomo, Ersilia
Community-Based Management of Child Malnutrition in Zambia: HIV/AIDS Infection and Other Risk Factors on Child Survival
title Community-Based Management of Child Malnutrition in Zambia: HIV/AIDS Infection and Other Risk Factors on Child Survival
title_full Community-Based Management of Child Malnutrition in Zambia: HIV/AIDS Infection and Other Risk Factors on Child Survival
title_fullStr Community-Based Management of Child Malnutrition in Zambia: HIV/AIDS Infection and Other Risk Factors on Child Survival
title_full_unstemmed Community-Based Management of Child Malnutrition in Zambia: HIV/AIDS Infection and Other Risk Factors on Child Survival
title_short Community-Based Management of Child Malnutrition in Zambia: HIV/AIDS Infection and Other Risk Factors on Child Survival
title_sort community-based management of child malnutrition in zambia: hiv/aids infection and other risk factors on child survival
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962207/
https://www.ncbi.nlm.nih.gov/pubmed/27376317
http://dx.doi.org/10.3390/ijerph13070666
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