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2,4,6-Tribromophenol Interferes with the Thyroid Hormone System by Regulating Thyroid Hormones and the Responsible Genes in Mice

2,4,6-Tribromophenol (TBP) is a brominated flame retardant (BFR). Based on its affinity for transthyretin, TBP could compete with endogenous thyroid hormone. In this study, the effects of TBP on the thyroid hormone system were assessed in mice. Briefly, animals were exposed to 40 and 250 mg/kg TBP....

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Detalles Bibliográficos
Autores principales: Lee, Dongoh, Ahn, Changhwan, Hong, Eui-Ju, An, Beum-Soo, Hyun, Sang-Hwan, Choi, Kyung-Chul, Jeung, Eui-Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962238/
https://www.ncbi.nlm.nih.gov/pubmed/27420076
http://dx.doi.org/10.3390/ijerph13070697