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Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial

BACKGROUND: Increasing levels of insecticide resistance as well as outdoor, residual transmission of malaria threaten the efficacy of existing vector control tools used against malaria mosquitoes. The development of odour-baited mosquito traps has led to the possibility of controlling malaria throug...

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Autores principales: Hiscox, Alexandra, Homan, Tobias, Mweresa, Collins K., Maire, Nicolas, Di Pasquale, Aurelio, Masiga, Daniel, Oria, Prisca A., Alaii, Jane, Leeuwis, Cees, Mukabana, Wolfgang R., Takken, Willem, Smith, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962350/
https://www.ncbi.nlm.nih.gov/pubmed/27460054
http://dx.doi.org/10.1186/s13063-016-1469-z
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author Hiscox, Alexandra
Homan, Tobias
Mweresa, Collins K.
Maire, Nicolas
Di Pasquale, Aurelio
Masiga, Daniel
Oria, Prisca A.
Alaii, Jane
Leeuwis, Cees
Mukabana, Wolfgang R.
Takken, Willem
Smith, Thomas A.
author_facet Hiscox, Alexandra
Homan, Tobias
Mweresa, Collins K.
Maire, Nicolas
Di Pasquale, Aurelio
Masiga, Daniel
Oria, Prisca A.
Alaii, Jane
Leeuwis, Cees
Mukabana, Wolfgang R.
Takken, Willem
Smith, Thomas A.
author_sort Hiscox, Alexandra
collection PubMed
description BACKGROUND: Increasing levels of insecticide resistance as well as outdoor, residual transmission of malaria threaten the efficacy of existing vector control tools used against malaria mosquitoes. The development of odour-baited mosquito traps has led to the possibility of controlling malaria through mass trapping of malaria vectors. Through daily removal trapping against a background of continued bed net use it is anticipated that vector populations could be suppressed to a level where continued transmission of malaria will no longer be possible. METHODS/DESIGN: A stepped wedge cluster-randomised trial design was used for the implementation of mass mosquito trapping on Rusinga Island, western Kenya (the SolarMal project). Over the course of 2 years (2013–2015) all households on the island were provided with a solar-powered mosquito trapping system. A continuous health and demographic surveillance system combined with parasitological surveys three times a year, successive rounds of mosquito monitoring and regular sociological studies allowed measurement of intervention outcomes before, during and at completion of the rollout of traps. Data collection continued after achieving mass coverage with traps in order to estimate the longer term effectiveness of this novel intervention. Solar energy was exploited to provide electric light and mobile phone charging for each household, and the impacts of these immediate tangible benefits upon acceptability of and adherence to the use of the intervention are being measured. DISCUSSION: This study will be the first to evaluate whether the principle of solar-powered mass mosquito trapping could be an effective tool for elimination of malaria. If proven to be effective, this novel approach to malaria control would be a valuable addition to the existing strategies of long-lasting insecticide-treated nets and case management. Sociological studies provide a knowledge base for understanding the usage of this novel tool. TRIAL REGISTRATION: Trialregister.nl: NTR3496 – SolarMal. Registered on 20 June 2012. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13063-016-1469-z) contains supplementary material, which is available to authorized users.
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spelling pubmed-49623502016-07-28 Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial Hiscox, Alexandra Homan, Tobias Mweresa, Collins K. Maire, Nicolas Di Pasquale, Aurelio Masiga, Daniel Oria, Prisca A. Alaii, Jane Leeuwis, Cees Mukabana, Wolfgang R. Takken, Willem Smith, Thomas A. Trials Study Protocol BACKGROUND: Increasing levels of insecticide resistance as well as outdoor, residual transmission of malaria threaten the efficacy of existing vector control tools used against malaria mosquitoes. The development of odour-baited mosquito traps has led to the possibility of controlling malaria through mass trapping of malaria vectors. Through daily removal trapping against a background of continued bed net use it is anticipated that vector populations could be suppressed to a level where continued transmission of malaria will no longer be possible. METHODS/DESIGN: A stepped wedge cluster-randomised trial design was used for the implementation of mass mosquito trapping on Rusinga Island, western Kenya (the SolarMal project). Over the course of 2 years (2013–2015) all households on the island were provided with a solar-powered mosquito trapping system. A continuous health and demographic surveillance system combined with parasitological surveys three times a year, successive rounds of mosquito monitoring and regular sociological studies allowed measurement of intervention outcomes before, during and at completion of the rollout of traps. Data collection continued after achieving mass coverage with traps in order to estimate the longer term effectiveness of this novel intervention. Solar energy was exploited to provide electric light and mobile phone charging for each household, and the impacts of these immediate tangible benefits upon acceptability of and adherence to the use of the intervention are being measured. DISCUSSION: This study will be the first to evaluate whether the principle of solar-powered mass mosquito trapping could be an effective tool for elimination of malaria. If proven to be effective, this novel approach to malaria control would be a valuable addition to the existing strategies of long-lasting insecticide-treated nets and case management. Sociological studies provide a knowledge base for understanding the usage of this novel tool. TRIAL REGISTRATION: Trialregister.nl: NTR3496 – SolarMal. Registered on 20 June 2012. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13063-016-1469-z) contains supplementary material, which is available to authorized users. BioMed Central 2016-07-26 /pmc/articles/PMC4962350/ /pubmed/27460054 http://dx.doi.org/10.1186/s13063-016-1469-z Text en © Hiscox et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Study Protocol
Hiscox, Alexandra
Homan, Tobias
Mweresa, Collins K.
Maire, Nicolas
Di Pasquale, Aurelio
Masiga, Daniel
Oria, Prisca A.
Alaii, Jane
Leeuwis, Cees
Mukabana, Wolfgang R.
Takken, Willem
Smith, Thomas A.
Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial
title Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial
title_full Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial
title_fullStr Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial
title_full_unstemmed Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial
title_short Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial
title_sort mass mosquito trapping for malaria control in western kenya: study protocol for a stepped wedge cluster-randomised trial
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962350/
https://www.ncbi.nlm.nih.gov/pubmed/27460054
http://dx.doi.org/10.1186/s13063-016-1469-z
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