DNA methylation of claudin-6 promotes breast cancer cell migration and invasion by recruiting MeCP2 and deacetylating H3Ac and H4Ac

BACKGROUND: Claudin-6 (CLDN6), a member of claudin transmembrane protein family, has recently been reported to be undetectable or at low levels in human breast cancer cell lines and tissues and plays a role in suppression of migration and invasion in breast cancer cells. In addition, it is reported...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yafang, Jin, Xiangshu, Li, Yanru, Ruan, Yang, Lu, Yan, Yang, Minlan, Lin, Dongjing, Song, Peiye, Guo, Yantong, Zhao, Shuai, Dong, Bing, Xie, Yinping, Dang, Qihua, Quan, Chengshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962420/
https://www.ncbi.nlm.nih.gov/pubmed/27461117
http://dx.doi.org/10.1186/s13046-016-0396-x

Ejemplares similares

Ejemplares similares