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Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent and mitochondrial pathways in mammalian hepatic stellate cells

BACKGROUND: Saikosaponin d (SSd) is one of the main active triterpene saponins in Bupleurum falcatum. It has a steroid-like structure, and is reported to have pharmacological activities, including liver protection in rat, cell cycle arrest and apoptosis induction in several cancer cell lines. Howeve...

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Detalles Bibliográficos
Autores principales:	Chen, Ming-Feng, Huang, S. Joseph, Huang, Chao-Cheng, Liu, Pei-Shan, Lin, Kun-I, Liu, Ching-Wen, Hsieh, Wen-Chuan, Shiu, Li-Yen, Chen, Chang-Han
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962421/ https://www.ncbi.nlm.nih.gov/pubmed/27461108 http://dx.doi.org/10.1186/s12885-016-2599-0

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