Gastric mucosa-associated lymphoid tissue lymphoma and Helicobacter pylori infection: a review of current diagnosis and management

Helicobacter pylori (H. pylori)-associated gastritis is one of the most common infectious diseases in the United States, China and worldwide. Gastric mucosa-associated tissue lymphoma (MALT lymphoma) is a rare mature B-cell neoplasm associated with H. pylori infection that is curable by antibiotics...

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Autores principales: Hu, Qinglong, Zhang, Yizhuo, Zhang, Xiaoyan, Fu, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962427/
https://www.ncbi.nlm.nih.gov/pubmed/27468353
http://dx.doi.org/10.1186/s40364-016-0068-1
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author Hu, Qinglong
Zhang, Yizhuo
Zhang, Xiaoyan
Fu, Kai
author_facet Hu, Qinglong
Zhang, Yizhuo
Zhang, Xiaoyan
Fu, Kai
author_sort Hu, Qinglong
collection PubMed
description Helicobacter pylori (H. pylori)-associated gastritis is one of the most common infectious diseases in the United States, China and worldwide. Gastric mucosa-associated tissue lymphoma (MALT lymphoma) is a rare mature B-cell neoplasm associated with H. pylori infection that is curable by antibiotics therapy alone. The pathological diagnosis of gastric MALT lymphoma can be reached by histological examination, immunohistochemical staining and B-cell clonality analysis. H. pylori eradication is the choice of therapy for early-stage gastric MALT lymphoma. High response rates and long-term survival have been reported in refractory and localized diseases treated with low-dose radiation therapy. Systemic chemotherapy is recommended for advanced-stage gastric MALT lymphoma and cases with large B-cell lymphoma transformation. Recent advances in the pathological diagnosis and management of gastric MALT lymphoma are reviewed in this article.
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spelling pubmed-49624272016-07-28 Gastric mucosa-associated lymphoid tissue lymphoma and Helicobacter pylori infection: a review of current diagnosis and management Hu, Qinglong Zhang, Yizhuo Zhang, Xiaoyan Fu, Kai Biomark Res Review Helicobacter pylori (H. pylori)-associated gastritis is one of the most common infectious diseases in the United States, China and worldwide. Gastric mucosa-associated tissue lymphoma (MALT lymphoma) is a rare mature B-cell neoplasm associated with H. pylori infection that is curable by antibiotics therapy alone. The pathological diagnosis of gastric MALT lymphoma can be reached by histological examination, immunohistochemical staining and B-cell clonality analysis. H. pylori eradication is the choice of therapy for early-stage gastric MALT lymphoma. High response rates and long-term survival have been reported in refractory and localized diseases treated with low-dose radiation therapy. Systemic chemotherapy is recommended for advanced-stage gastric MALT lymphoma and cases with large B-cell lymphoma transformation. Recent advances in the pathological diagnosis and management of gastric MALT lymphoma are reviewed in this article. BioMed Central 2016-07-27 /pmc/articles/PMC4962427/ /pubmed/27468353 http://dx.doi.org/10.1186/s40364-016-0068-1 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Hu, Qinglong
Zhang, Yizhuo
Zhang, Xiaoyan
Fu, Kai
Gastric mucosa-associated lymphoid tissue lymphoma and Helicobacter pylori infection: a review of current diagnosis and management
title Gastric mucosa-associated lymphoid tissue lymphoma and Helicobacter pylori infection: a review of current diagnosis and management
title_full Gastric mucosa-associated lymphoid tissue lymphoma and Helicobacter pylori infection: a review of current diagnosis and management
title_fullStr Gastric mucosa-associated lymphoid tissue lymphoma and Helicobacter pylori infection: a review of current diagnosis and management
title_full_unstemmed Gastric mucosa-associated lymphoid tissue lymphoma and Helicobacter pylori infection: a review of current diagnosis and management
title_short Gastric mucosa-associated lymphoid tissue lymphoma and Helicobacter pylori infection: a review of current diagnosis and management
title_sort gastric mucosa-associated lymphoid tissue lymphoma and helicobacter pylori infection: a review of current diagnosis and management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962427/
https://www.ncbi.nlm.nih.gov/pubmed/27468353
http://dx.doi.org/10.1186/s40364-016-0068-1
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AT zhangxiaoyan gastricmucosaassociatedlymphoidtissuelymphomaandhelicobacterpyloriinfectionareviewofcurrentdiagnosisandmanagement
AT fukai gastricmucosaassociatedlymphoidtissuelymphomaandhelicobacterpyloriinfectionareviewofcurrentdiagnosisandmanagement

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