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The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine
BACKGROUND: The diversity of clinical tumor profiling approaches (small panels to whole exomes with matched or unmatched germline analysis) may engender uncertainty about their benefits and liabilities, particularly in light of reported germline false positives in tumor-only profiling and use of glo...
Autores principales: | Garofalo, Andrea, Sholl, Lynette, Reardon, Brendan, Taylor-Weiner, Amaro, Amin-Mansour, Ali, Miao, Diana, Liu, David, Oliver, Nelly, MacConaill, Laura, Ducar, Matthew, Rojas-Rudilla, Vanesa, Giannakis, Marios, Ghazani, Arezou, Gray, Stacy, Janne, Pasi, Garber, Judy, Joffe, Steve, Lindeman, Neal, Wagle, Nikhil, Garraway, Levi A., Van Allen, Eliezer M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962446/ https://www.ncbi.nlm.nih.gov/pubmed/27460824 http://dx.doi.org/10.1186/s13073-016-0333-9 |
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