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GAGA factor, a positive regulator of global gene expression, modulates transcriptional pausing and organization of upstream nucleosomes
BACKGROUND: Genome-wide studies in higher eukaryotes have revealed the presence of paused RNA polymerase II (RNA-Pol) at about 30–50 bp downstream of the transcription start site of genes involved in developmental control, cell proliferation and intercellular signaling. Promoter-proximal pausing is...
Autores principales: | Tsai, Shih-Ying, Chang, Yuh-Long, Swamy, Krishna B. S., Chiang, Ruei-Lin, Huang, Der-Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962548/ https://www.ncbi.nlm.nih.gov/pubmed/27468311 http://dx.doi.org/10.1186/s13072-016-0082-4 |
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