Cargando…
Vascular disruptive agent OXi4503 and anti-angiogenic agent Sunitinib combination treatment prolong survival of mice with CRC liver metastasis
BACKGROUND: Preclinical research indicate that vascular disrupting agent (VDA) treatment induces extensive tumor death but also a systemic mobilization of bone marrow derived cells including endothelial progenitor cells (EPC) leading to revascularization and renewed growth within the residual tumor....
Autores principales: | Nguyen, Linh, Fifis, Theodora, Christophi, Christopher |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962549/ https://www.ncbi.nlm.nih.gov/pubmed/27460820 http://dx.doi.org/10.1186/s12885-016-2568-7 |
Ejemplares similares
-
Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor
por: Fifis, Theodora, et al.
Publicado: (2013) -
Preclinical Activity of the Vascular Disrupting Agent OXi4503 against Head and Neck Cancer
por: Bothwell, Katelyn D., et al.
Publicado: (2016) -
Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments
por: Nguyen, Linh, et al.
Publicado: (2012) -
Evaluation of cell death mechanisms induced by the vascular disrupting agent OXi4503 during a phase I clinical trial
por: Cummings, J, et al.
Publicado: (2012) -
The kallikrein-Kinin system modulates the progression of colorectal liver metastases in a mouse model
por: da Costa, Patricia Luiza Nunes, et al.
Publicado: (2018)