Indirubin-3′-monoxime suppresses amyloid-beta-induced apoptosis by inhibiting tau hyperphosphorylation

Indirubin-3′-monoxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease. Here, we found that indirubin-3′-monoxime improved the morphology and increased the survival rate of SH-SY5Y cells exposed to amyloid-...

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Detalles Bibliográficos
Autores principales: Zhang, Shu-gang, Wang, Xiao-shan, Zhang, Ying-dong, Di, Qing, Shi, Jing-ping, Qian, Min, Xu, Li-gang, Lin, Xing-jian, Lu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962599/
https://www.ncbi.nlm.nih.gov/pubmed/27482230
http://dx.doi.org/10.4103/1673-5374.184500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962599/
https://www.ncbi.nlm.nih.gov/pubmed/27482230
http://dx.doi.org/10.4103/1673-5374.184500

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