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DNA damage tolerance by recombination: Molecular pathways and DNA structures
Replication perturbations activate DNA damage tolerance (DDT) pathways, which are crucial to promote replication completion and to prevent fork breakage, a leading cause of genome instability. One mode of DDT uses translesion synthesis polymerases, which however can also introduce mutations. The oth...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962778/ https://www.ncbi.nlm.nih.gov/pubmed/27236213 http://dx.doi.org/10.1016/j.dnarep.2016.05.008 |