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Impact of vaccination on meningococcal epidemiology

Neisseria meningitidis may cause invasive disease (meningitis and sepsis), leading to considerable disease burden and mortality. However, effective vaccines are available against most pathogenic serogroups. Large-scale vaccination campaigns with the MCC vaccine conducted in UK and with MenAfriVac in...

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Autores principales: Stefanelli, Paola, Rezza, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962961/
https://www.ncbi.nlm.nih.gov/pubmed/26512927
http://dx.doi.org/10.1080/21645515.2015.1108502
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author Stefanelli, Paola
Rezza, Giovanni
author_facet Stefanelli, Paola
Rezza, Giovanni
author_sort Stefanelli, Paola
collection PubMed
description Neisseria meningitidis may cause invasive disease (meningitis and sepsis), leading to considerable disease burden and mortality. However, effective vaccines are available against most pathogenic serogroups. Large-scale vaccination campaigns with the MCC vaccine conducted in UK and with MenAfriVac in the Sahel have clearly demonstrated the direct and indirect effect of immunization programmes on disease and carriage. Moreover, the introduction of novel subcapsular vaccines against serogroup B, which may cross-protect against other serogroups, is likely to have a further effect on trends. Accurate data collection is key to elaborate vaccination strategies able to reduce meningococcal disease burden through direct protection and herd immunity.
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spelling pubmed-49629612016-08-17 Impact of vaccination on meningococcal epidemiology Stefanelli, Paola Rezza, Giovanni Hum Vaccin Immunother Reviews Neisseria meningitidis may cause invasive disease (meningitis and sepsis), leading to considerable disease burden and mortality. However, effective vaccines are available against most pathogenic serogroups. Large-scale vaccination campaigns with the MCC vaccine conducted in UK and with MenAfriVac in the Sahel have clearly demonstrated the direct and indirect effect of immunization programmes on disease and carriage. Moreover, the introduction of novel subcapsular vaccines against serogroup B, which may cross-protect against other serogroups, is likely to have a further effect on trends. Accurate data collection is key to elaborate vaccination strategies able to reduce meningococcal disease burden through direct protection and herd immunity. Taylor & Francis 2015-10-29 /pmc/articles/PMC4962961/ /pubmed/26512927 http://dx.doi.org/10.1080/21645515.2015.1108502 Text en © 2016 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Reviews
Stefanelli, Paola
Rezza, Giovanni
Impact of vaccination on meningococcal epidemiology
title Impact of vaccination on meningococcal epidemiology
title_full Impact of vaccination on meningococcal epidemiology
title_fullStr Impact of vaccination on meningococcal epidemiology
title_full_unstemmed Impact of vaccination on meningococcal epidemiology
title_short Impact of vaccination on meningococcal epidemiology
title_sort impact of vaccination on meningococcal epidemiology
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962961/
https://www.ncbi.nlm.nih.gov/pubmed/26512927
http://dx.doi.org/10.1080/21645515.2015.1108502
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