Levels of DNA Methylation Vary at CpG Sites across the BRCA1 Promoter, and Differ According to Triple Negative and “BRCA-Like” Status, in Both Blood and Tumour DNA

Triple negative breast cancer is typically an aggressive and difficult to treat subtype. It is often associated with loss of function of the BRCA1 gene, either through mutation, loss of heterozygosity or methylation. This study aimed to measure methylation of the BRCA1 gene promoter at individual Cp...

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Detalles Bibliográficos
Autores principales: Daniels, Sarah L., Burghel, George J., Chambers, Philip, Al-Baba, Shadi, Connley, Daniel D., Brock, Ian W., Cramp, Helen E., Dotsenko, Olena, Wilks, Octavia, Wyld, Lynda, Cross, Simon S., Cox, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963032/
https://www.ncbi.nlm.nih.gov/pubmed/27463681
http://dx.doi.org/10.1371/journal.pone.0160174

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