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Loss of Renal Tubular PGC-1α Exacerbates Diet-Induced Renal Steatosis and Age-Related Urinary Sodium Excretion in Mice

The kidney has a high energy demand and is dependent on oxidative metabolism for ATP production. Accordingly, the kidney is rich in mitochondria, and mitochondrial dysfunction is a common denominator for several renal diseases. While the mitochondrial master regulator peroxisome proliferator-activat...

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Detalles Bibliográficos
Autores principales:	Svensson, Kristoffer, Schnyder, Svenia, Cardel, Bettina, Handschin, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963111/ https://www.ncbi.nlm.nih.gov/pubmed/27463191 http://dx.doi.org/10.1371/journal.pone.0158716

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