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Kinetics of initiating polypeptide elongation in an IRES-dependent system
The intergenic IRES of Cricket Paralysis Virus (CrPV-IRES) forms a tight complex with 80S ribosomes capable of initiating the cell-free synthesis of complete proteins in the absence of initiation factors. Such synthesis raises the question of what effect the necessary IRES dissociation from the tRNA...
Autores principales: | Zhang, Haibo, Ng, Martin Y, Chen, Yuanwei, Cooperman, Barry S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963199/ https://www.ncbi.nlm.nih.gov/pubmed/27253065 http://dx.doi.org/10.7554/eLife.13429 |
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