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The expanding regulatory universe of p53 in gastrointestinal cancer

Tumor suppresser gene TP53 is one of the most frequently deleted or mutated genes in gastrointestinal cancers. As a transcription factor, p53 regulates a number of important protein coding genes to control cell cycle, cell death, DNA damage/repair, stemness, differentiation and other key cellular fu...

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Detalles Bibliográficos
Autores principales: Fesler, Andrew, Zhang, Ning, Ju, Jingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963207/
https://www.ncbi.nlm.nih.gov/pubmed/27508057
http://dx.doi.org/10.12688/f1000research.8363.1

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