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Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation
Inflammasomes are high-molecular-weight protein complexes that are formed in the cytosolic compartment in response to danger- or pathogen-associated molecular patterns. These complexes enable activation of an inflammatory protease caspase-1, leading to a cell death process called pyroptosis and to p...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000Research
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963208/ https://www.ncbi.nlm.nih.gov/pubmed/27508077 http://dx.doi.org/10.12688/f1000research.8614.1 |